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Instrumentation Engineer, Optics & Fluidics (Hyb & Seq)

Job Summary:

We are seeking an Engineer to join our Research and Development group.  In this role you will work on the development of instrumentation and consumables for new genomic tools.  See recently released Sprint TM ( In particular, this position is focused on the development of hardware related to the recently announced Hyb & Seq TM technology (NGS), a novel single-molecule hybridization-based sequencing chemistry. The work is highly interdisciplinary and will involve working closely with scientists, fluidics engineers, software engineers, and external OEM manufacturers.  The applicant will be expected to contribute to the development of instrument/consumable prototypes for feasibility and aid in the testing of these systems. Additionally, the applicant will be expected to work with OEM partners and assist in the development of the new systems up to and through commercialization and transfer to manufacturing. The applicant will be expected to have strong verbal and written communication skills and will be expected to manage communication with OEM partners.   

Essential Functions:

  • Develop instrument system, meeting commercial goals and design requirements
  • Design hardware related to imaging and fluidics
  • Automation of motion, imaging, and fluidic control
  • Strong knowledge of SolidWorks

Requirements (Education, Experience, Specific Skills):

  • Degree in mechanical, electrical, bioengineering, physics, bio-physics or related field
  • PhD. + 4-6, M.S + 6-8, or B.S. + 8-12 years experience working in the genomics and proteomics and imaging tools industry
  • Experience with design and development of commercial instrumentation
  • Experience with design and automation of optical and fluidic systems
  • Experience with design and development of consumables
  • Instrument prototyping through development and assembly of breadboard systems
  • Automation of repetitive activities through script-level programing and/or C.
  • Strong engineering or biophysics background in the design and analysis of mechanical, chemical, and biological systems
  • A hands-on orientation toward experimentation and rapid prototype development
  • Ability to work both independently and closely in collaboration with a core team
  • Excellent verbal and written communication skills

Additional qualifications include:

  • Experience with fluorescent microscopy
  • Experience with design/selection of hardware to control microfluidics: pumps, valves, and manifolds.
  • Experience with fluidics/microfluidics and/or pipetting robots
  • Experience with hardware/consumable development for genomics
  • Flow cell design and fabrication
  • Experience operating machine shop equipment: Mill, lathe, laser cutter, 3D printer, etc.
  • Wet bench skills


  • See benefits at NanoString
  • NanoString is an EOE
  • NanoString participates in E-Verify. E-Verify is a web-based system that allows an employer to determine an employee's eligibility to work in the US using information reported on an employee's Form I-9. The E-Verify system confirms eligibility with both the Social Security Administration (SSA) and Department of Homeland Security (DHS). For more information, please go to the USCIS E-Verify website.
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