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Mechanical Engineer II

Job Summary:

We are seeking an Engineer to join our Research and Development group.  In this role you will work on the development of new genomic tools that consist of instrumentation, consumables, and chemistry. In particular, this position is focused on the development of the recently announced Hyb & Seq TM technology (NGS), a novel single-molecule hybridization-based sequencing chemistry. The work is highly interdisciplinary will involve working closely with biologists, scientists, software engineers, and external OEM manufacturers.  The applicant will be expected to have strong verbal and written communication skills and will be expected to manage communication with OEM partners.  The position will involve development of instrumentation as well as testing of designs: both fluidic and optical systems. The applicant will be expected to help automate Hyb and Seq sample prep by prototyping hardware to run microfluidic cards, as well as, support optical development efforts

Essential Duties:

  • Develop commercial instrument systems
  • Design hardware related to imaging and fluidics
  • Rapid prototyping
  • Strong Knowledge of Solidworks


  • Degree in mechanical, mechatronic, optical, or related engineering field
  • B.S. 4+, M.S + 4-6 years experience
  • Experience with design mechanisms and instrument systems
  • Experience with design of optical systems
  • Experience with design and automation of fluidic systems
  • Instrument prototyping through development and assembly of breadboard systems
  • A hands-on orientation toward experimentation and rapid prototype development
  • Ability to carry out experiments to verify performance of designs
  • Ability to work both independently and closely in collaboration with a core team
  • Excellent verbal and written communication skills
  • Strong proficiency in CAD (Solidworks preferred)

Additional qualifications include:

  • Experience designing mechanical components for optic assemblies
  • Experience with fluidics/microfluidics and or pipetting robots
  • Experience with microscopy
  • Experience with design/selection of hardware to control microfluidics: pumps, valves, and manifolds.
  • Experience with hardware/consumable development for genomics
  • Flow cell design and fabrication
  • Experience operating machine shop equipment: Mill, lathe, laser cutter, 3D printer, etc.
  • Automation of repetitive activities through script-level programing and/or C.


  • See benefits at NanoString
  • NanoString is an EOE
  • NanoString participates in E-Verify. E-Verify is a web-based system that allows an employer to determine an employee's eligibility to work in the US using information reported on an employee's Form I-9. The E-Verify system confirms eligibility with both the Social Security Administration (SSA) and Department of Homeland Security (DHS). For more information, please go to the USCIS E-Verify website.


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